RAS proteins, their regulators and the downstream enzymes that they control are activated in many tumour types by a variety of mechanisms, including oncogenic mutation of RAS genes. They are crucial ...
The RAS superfamily of GTPases includes five major subfamilies of monomeric guanine nucleotide binding proteins (RAS, RHO, RAB, RAN and ARF), which possess GDP/GTP-binding and intrinsic GTPase ...
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