Illustration of a spatial imprint of captured transcripts by Nova-ST, along with the localization of binned clustering, for a coronal section of the mouse brain. The illustration below the brain ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

Spatial transcriptomics has emerged as a powerful tool for in situ analysis of gene expression within tissues. However, current technologies still face several challenges, including high costs, ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers critical insight ...

A team of researchers from the lab of Prof. Stein Aerts (VIB-KU Leuven) presents Nova-ST, a new spatial transcriptomics technique that promises to transform gene expression profiling in tissue samples ...