A newly discovered molecule, OLE, restored the brain's immune cells to a more protective state in Alzheimer's disease models.

Researchers have successfully demonstrated how astroglia—cells that support the functioning of the brain—can be reprogrammed into cells resembling interneurons. The research, published in Science ...

A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling ...

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal ageing — inevitable with ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

Blindness itself might become, at least in certain cases, partially reversible. This potential future stems from one of the ...

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible. But the brain is not static; neurons continually adjust the strength of their ...

A newly discovered molecule, OLE, restored the brain’s immune cells to a more protective state in Alzheimer’s disease models. The treatment reduced the accumulation of toxic plaques and improved ...